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Jutabha et al., 2011)

CpG methylation induces histone deacetylation, chromatin remodeling, and gene silencing through a transcription repressive complex, which includes SMRT (silencing mediators of retinoic acid and thyroid receptor), mSin3a, RbAp46/48, and the formation around mSin3a The two histone deacetylases HDAC1 and HDAC2

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Techniques such as TMS have shown the ability to non-invasively induce electrochemical currents in specific brain regions, either enhancing or suppressing neural activity depending on the frequency and intensity of the magnetic pulses (Turner et al., 2014)