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That dual action may give the drug a bit more juice

Aside from antioxidant metabolism and regulation in response to elevated ROS, cells also recruit components of the DNA damage response (DDR) pathway to cope with the potential damaging effect of free radicals on DNA 29,43

But scientists say that if orforglipron and similar drugs in development reach the market, they could aid efforts to tackle obesity and diabetes, including in LMICs where the prevalence of such conditions is rising rapidly

Insulin resistance is also a risk factor for Alzheimers disease, and taking myo-inositol and d-chiro-inositol and reducing insulin resistance may protect against dementia