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Following chronic (6 week) feeding with an ethanol-containing liquid diet, the Gclm KO mice were unexpectedly found to be protected against steatosis despite showing increased oxidative stress (as reflected in elevated levels of CYP2E1 and protein carbonyls)

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This approach should be associated with the environmental one, which consists of reducing exposure to toxic substances and choosing a healthy lifestyle: a balanced diet, regular and moderate physical activity, and continuous stress management

10.1039/c7tx00340d 13 AwasthiY