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McCubrey JA, Lahair MM, Franklin RA
Fuchs S, Ghanaati S, Orth C, Barbeck M, Kolbe M, Hofmann A
It catalyzes the conversion of GSSH to GSH and sulfite (Figure 2g) (Figure 2h) ( 2 S is a toxic gas that binds to the heme of cytochrome c oxidase and inhibits mitochondrial respiration, it also serves as an electron donor for the mitochondrial electron transport chain ( 2 S and RSS (primarily GSSH) levels
The TMA consisted of 109 primary tumours collected before chemotherapy, 19 primary tumours collected after chemotherapy, and 28 recurrent tumours that were subsequently treated with second-line chemotherapy
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