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The primary GH pulse occurs during stage 3 deep sleep, and if sleep architecture is disrupted by hot flashes, night sweats, or anxiety, the GH response to secretagogues is blunted

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VITAMIN D Vitamin D is a steroid hormone whose function is regulated by the vitamin D receptor (VDR), which is found in various tissues of the human body, including the ovaries, playing an important role in female reproductive physiology 13