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Another small, randomized, double-blind trial in 93 individuals with low vitamin D status found no additional benefit of B-vitamin supplementation (50 mg/day of vitamin B6, 0.5 mg/day of folic acid, and 0.5 mg/day of vitamin B 12 ) on markers of bone health over a one-year period beyond that associated with vitamin D and calcium supplementation

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However, the rates of D3 top-quality embryos, blastocyst formation, and usable blastocysts-the max did not show any improvement

However, it is FDA-approved specifically for the treatment of lipodystrophy in HIV-infected patients to reduce excess abdominal fat