When melanin production increases or becomes irregular, the skin can appear darker or develop hyperpigmentation
Furthermore, the increased ejaculatory latency induced by SSRIs may result in a number of negative effects on semen quality, including higher DNA fragmentation in sperm, increased prolactin (PRL) levels, decreased testosterone levels, and sexual dysfunction in some men, potentially inhibiting male reproduction (Figure 3) ( 5 Effects of SSRIs on the reproductive system of aquatic organisms SSRIs are a major class of drugs of environmental concern, and fluoxetine, a psychoactive agent, is one of the best-selling prescription antidepressants in the world, which increases the likelihood of aquatic environmental contamination through municipal, industrial, and hospital discharges, potentially inducing sublethal effects in non-target species
If these medications are going to reach the people who could genuinely benefit from them, it is important they are properly understood and prescribed safely
Clin Neuropharmacol 2013;36:185-92
