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Bioinformatics (Oxford England) , 35 (21), 43564363

doi: 10.3389/fragi.2025.1696473 Received 31 August 2025 Revised 28 November 2025 Accepted 04 December 2025 Published 06 January 2026 Volume 6 - 2025 Edited by Marco P Brotto, University of Texas at Arlington, United States Reviewed by Eduardo Abreu, University of MissouriKansas City, United States Andr Luis Shinohara, Faculdade de Odontologia da Universidade de So Paulo, Brazil Updates Copyright 2026 Da Silva Rodrigues, Lopes da Silva, Crystine da Silva Sobrinho, Benjamim, Abud, Ortiz, Cristini de Freitas and Bueno Jnior