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Cell 2011, 22 (18), 34983507

The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians, 38(4), 239246

If gastrointestinal symptoms are problematic at night, consider: Eating your evening meal at least 34 hours before bedtime Consuming smaller, more frequent meals throughout the day Avoiding rich, fatty, or spicy foods in the evening, which may exacerbate reflux or nausea Address gastrointestinal side effects proactively

As shown in Figures 3AC, when mice fed on a HFD, fasting blood glucose and insulin levels both were significantly increased, compared to NCD mice, thereby resulting in a higher HOMA-IR value (7.95 vs 5.14)