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The Mesolimbic System: Lowering the Reward Volume If the hypothalamus regulates the homeostatic stomach hunger that tells you your body needs fuel, you can think of the mesolimbic system as driving your hedonic brain hunger. The mesolimbic system includes the ventral tegmental area (VTA) and nucleus accumbens (NAc)

Avoid severely restrictive plans that eliminate entire food groups and make it hard to meet your bodys needs

Attia is also the host of The Drive podcast and author of the best-selling book Outlive

For more detail on the broader comfort question, are Ozempic injections painful is a useful companion read