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The STEP 1 trial (N=1,961) published in the New England Journal of Medicine in 2021 (DOI: 10.1056/NEJMoa2032183) demonstrated 14.9% mean body weight reduction with semaglutide 2.4mg weekly versus 2.4% with placebo over 68 weeks
However, studies on oral semaglutide (like the brand-name Rybelsus, which is FDA-approved for type 2 diabetes) suggest that it can be effective
B5 is crucial for the production of energy
This can be very useful for protocols requiring smaller, more precise doses, as it makes measuring them physically easier by increasing the volume you need to draw
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