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Side effects to watch for at any dose step For Rybelsus and other semaglutide products, important safety considerations include the boxed warning related to thyroid C-cell tumors observed in rodents and contraindications for patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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Factors such as hormonal imbalances, insulin resistance, poor sleep, chronic stress, or certain prescription medications can all affect your ability to lose weight