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In addition to LPS, under the pathological conditions of atherosclerosis, increased production of the metabolic product trimethylamine N-oxide (TMAO) by the gut microbiota can promote fosters leukocyte adherence and movement toward the vascular wall by upregulating the expression of cell adhesion molecules in ECs, as well as activate the NLR family pyrin domain containing 3 (NLRP3) inflammasome to enhance inflammatory responses, thereby destabilizing atherosclerotic plaques (Wang C

You can support natural GLP-1 secretion by: Eating more protein and fiber (e.g., legumes, whole grains, eggs, yogurt) Consuming healthy fats (e.g., avocado, olive oil, nuts) Exercising regularly Avoiding rapid spikes in blood sugar (e.g., reduce processed carbs and sugar) Intermittent fasting or time-restricted eating may also help improve GLP-1 levels and sensitivity Is GLP-1 safe for long-term use

Beyond nausea, be prepared for these possibilities