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MacKie, R

Lipoic acid is covalently bound to certain proteins, which function as part of essential mitochondrial multienzyme complexes involved in energy and amino acid metabolism (see Biological Activities)

Fagher B, Thysell H, Nilsson-Ehle P et al (1982) The effect of D, L-carnitine supplementation on muscle metabolism, neuropathy, cardiac and hepatic function in hemodialysis patients

In one study, dysbiosis in individuals exposed to chronic stress was linked to increased intestinal permeability, also known as leaky gut. This permeability allows bacterial endotoxins to enter the bloodstream, promoting systemic inflammation