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[5] [6] Tirzepatide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis

If you're traveling or anticipating a scheduling conflict, plan ahead with your healthcare provider

an=16 Cmax- measured peak concerntraion Tmax- observed time of peak concentration t1/2- elimination half-life, calculated by 0.693/Kelim AUC0-24- area under the concentrarion- time curve calculated by the linear trapezoidal rule (Time 0 to 24 hours) CL/F- apparent clearance Distribution Etonogestrel, the active metabolite of desogestrel, was found to be 99% protein bound, primarily to sex hormone-binding globulin (SHBG)

SURPASS trials for tirzepatide) show neutral or favorable cardiac effects when used appropriately