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doi: 10.1016/j.rmed.2020.106063

Hemoglobin breakdown : Each RBC contains hemoglobin (Hb), 1 which is broken down into: Globin degraded into amino acids (reused) Heme further metabolized into: 2 Iron (Fe) stored as ferritin or hemosiderin or recycled for new RBC synthesis Protoporphyrin ring converted to biliverdin by the enzyme heme oxygenase 3 Biliverdin reduced to unconjugated (indirect) bilirubin by biliverdin reductase 4 Unconjugated bilirubin in plasma: Unconjugated bilirubin is lipophilic and water-insoluble

Glutathione is a critical player in numerous bodily processes, including detoxification, antioxidant protection, and immune system support

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