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TangHDonahooWTSvenssonMShaabanCESmithGJaffeeMSet al

However, researchers should note that longer trials with ipamorelin may cause side effects typical for ghrelin mimetics, such as water retention and increased appetite [23]

Peer review Peer review information Nature Reviews Endocrinology thanks Juan Pablo Frias, Baptist Gallwitz and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

The current review will focus on four main areas: (1) general description of oxidative stress markers in SLE, (2) alteration of redox state and complication of disease (3) role of redox mechanisms in the initiation and execution phases of apoptosis, and (4) intracellular glutathione and its checkpoints with lymphocyte apoptosis represent novel targets for pharmacological intervention in SLE