Loss of membrane integrity during ferroptosis is caused by lipid peroxidation mediated by oxidoreductases, which depend on iron, ROS, and polyunsaturated-fatty-acid-containing phospholipids (PUFA-PLs)
However, researchers are interested in its application in other areas of the bodyparticularly in regards to wound healing, neuroprotection, and muscle and tissue growth
The biological processes associated with these human liver proteins identified by PANTHER GO Slim analysis, include but are not limited to, iron ion transport, heme metabolic process, intracellular iron ion homeostasis, tricarboxylic acid cycle, transition metal ion transport, complement activation, and anti-bacterial humoral immune response
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