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For non-diabetic research subjects, fasting glucose normalization was observed within the first 48 weeks of the escalation phase, even before maximum dose was reached

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also showed the same trend in knee symptoms and daily activity progression using the mean KOOS score in ten participants with degenerative meniscus tears without osteoarthritis according to Stoller classification after 3 months and 6 months of follow up (i.e., KOOS: 56.6 15.7 baseline, 70.2 16.8 post- 3 months, 72.7 18.5 post- 6 months, p = 0.0007)