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This approach is particularly important because there is no established protocol for discontinuing GLP-1 therapy in the medical literature

Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

Always check with your specific provider and ask about patient assistance programs offered by pharmaceutical companies

Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord