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Compound 102 suppressed production of lipid ROS as well ( Supplementary Figure S9 )

Several studies have reported a prevalence of asthma ranging from 20 to 50% in individuals with homozygous (ZZ) and heterozygous (SZ) A1ATD ( It is hypothesized that augmentation therapy could improve inflammation, reduce bronchial hyperresponsiveness, and prevent the development of chronic airway changes in these patients

Faghiri, Z

This becomes especially relevant when there are superior options like administration by the orobuccal route, whereby high serum levels are rapidly achieved

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