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While strict inclusion criteria ensured methodological quality, they may have reduced the breadth of eligible evidence, limiting the scope of subgroup analyses and the generalizability of certain findings

Outstanding Questions GLP-1RA is a new type of drug for the treatment of T2MD

Neuroprotective effects of GLP-1R agonism GLP-1R agonists improve cerebral blood flow (CBF): By enhancing neurovascular coupling, these drugs ensure that blood flow is properly regulated in response to brain activity, improving overall brain function, particularly in obesity and metabolic disorders

We dont know yet if it is better or worse, Jay says