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Activated microglia release pro-inflammatory cytokines, reactive oxygen species, and neurotoxic mediators that exacerbate vascular and white matter injury

What it is not is a pharmaceutical drug with decades of human clinical trial data, a guaranteed outcome, or a simple regulatory situation - and this guide has not pretended any of those things

You may receive B12 injections every 2 days to every 4 days.

Importantly, 70-80% of participants achieved at least 10% weight loss (the threshold for clinically meaningful benefits), and 50-60% achieved at least 20% weight loss (approaching surgical weight loss results without surgery)