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Retatrutide (Retara), a triple GIP/GLP-1/glucagon agonist, produced the highest mean weight loss in clinical trials (24.2% at 48 weeks)

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Reduce the dose temporarily and re-attempt the increase later

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Figure 5 This chapter investigates the mechanisms underlying BA metabolic dysregulation in gout

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Yang C, Hawkins KE, Dor S, Candelario-Jalil E (2019) Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

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