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It: Stimulates insulin secretion (only when glucose is elevated) Suppresses glucagon Slows gastric emptying Reduces appetite Promotes satiety Due to these effects, GLP-1 plays a central role in blood glucose regulation, weight management, and metabolic health
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GLP-1 side effects should be discussed with a doctor when nausea, constipation, vomiting, reflux, fatigue, dizziness, abdominal pain, dehydration, or poor intake interferes with daily life, prevents the patient from eating enough protein or drinking enough fluid, worsens after a dose increase, persists for more than a short adjustment period, or feels severe or unusual