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It makes it ineffective

Defined as the state in which a cell stops reproducing, cellular senescence is associated with many of the health troubles we associate with advanced age dementia, arthritis, and cardiovascular diseases and shortened telomeres may be its main contributing factor.12 13 In theory, by lengthening your telomeres with epitalon, you could increase your cellular lifespan and, therefore, ward off the deleterious effects of growing older

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Years of applying cosmetic and other makeup containing a high concentration of dyes and metal salts can also produce extensive damage and sagging