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Since commercial patients tend to be younger and healthier than Medicare beneficiaries, early GLP-1 use is reinforcing its role as a reliable foundation for diabetes care and could be a contributing factor to rising rates of monotherapy

Compounded semaglutide is not FDA-approved

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Tirzepatide and semaglutide are generally safe, but they may not be suitable for everyone, including: People with a personal or family history of thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2) People with a personal or family history of pancreatitis People with known hypersensitivity to any component of the medication People who are pregnant, breastfeeding, and planning to become pregnant Always consult a healthcare provider before starting a new medication