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The product has demonstrated bioequivalence to the reference (innovator) drug, with its performance further validated through phase III clinical studies conducted in direct comparison

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When considering which patients would be least suitable for treatment with semaglutide, the clinical experts deferred to the product monograph for absolute contraindications and patients with potential increased risk of adverse effects (e.g., history of pancreatitis, gallbladder disease, diabetic retinopathy, severe renal impairment, gastrointestinal conditions)