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Among the patients with total gastrectomy, the risk of T2D was significantly increased in those who did not receive vitamin B12 supplementation (AHR=1.60, 95% CI=1.33-1.92), whereas the risk of T2D was not significant in those who received continuous vitamin B12 supplementation after gastrectomy (AHR=0.7, 95% CI=0.49- 1.01)

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However, our study also had shortcomings: due to the limitations of our study design, we could not distinguish the effect of GLP-1/GIP dual-receptor activation and weight loss on bone mass in this experiment

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