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This membrane-bound form of IGFBPs plays a regulatory role in IGF-1 signaling, either by modulating IGF-1 binding to its receptors or by initiating distinct signaling pathways, thereby fine-tuning cellular responses (Zhang et al., 2023)

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The robust reduction in non-cardiovascular death, and particularly infections deaths, was surprising, Benjamin Scirica, lead author of one of the Select studies, told The Guardian

Transmission of light to the young primate retina: possible implicationsfor the formation of lipofuscin