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However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)

In a retrospective series of over 2,000 compounded lipotropic injections, the incidence of systemic hypersensitivity was below 0.1 percent, yet clinicians should maintain readiness to administer intramuscular epinephrine and transfer patients to higher-level care when indicated

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