SmartBrace: The Technology You KNEEd, Rachel Naidich, Kshamata Neupane, Ish Sethi, Matthew Trang, Rebecca Woodhouse, Nadia Ali, Satoshi Sato, Alexa Williams, Marrisa Howard, Alessandra Luchini, Lance A
Through creatine recycling via creatine kinase, ingestion of 3 g of creatine monohydrate can help store 50 kcal energy in the skeletal muscle of a 70-kg person for supporting a 60-min intensive exercise (i.e., 483 mmol creatine phosphate/whole-body skeletal muscle/min 20/142 = 68 mmol = 68 mmol 12.3 kcal/mol 0.001 60 min = 50 kcal)
doi: 10.1016/j.diabres.2005.05.004
In parallel, there is growing focus on small molecule GLP-1R agonists , which have the potential to be administered orally, produced more cost-effectively, and offer improved stability and pharmacokinetic profiles