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ABCA1 is pivotal for HDL-C biogenesis and cholesterol efflux, whereas SR-B1 mediates uptake of HDL cholesteryl esters [37,38]

The acetylated version of glutathione may help to detoxify and repair cellular damage

As indicated for the development of testing strategies, the chemical applicability domain needs to reflect the chemical sector universe for which the test method will be utilised, and the chemicals selected and subsequently tested can start to gauge the relative points of departure for the mechanism and/or endpoints under investigation