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Mean Elimination Half-Life (t): In rats, the average elimination half-life after a single intravenous (IV) administration is 15.2 minutes

78 HP 160 CAGRILINTIDE Long-Acting Amylin Analog ALIASES Cagrilintide, AM833, long-acting amylin analog CLASS Synthetic amylin analog once-weekly dual amylin/calcitonin agonist FORMULA CHNO (approx) SEQUENCE 37-residue amylin analog with C20-fatty-acid albumin tether HALF-LIFE ~7 days (once-weekly dosing) ROUTES Subcutaneous (Phase 2/3 clinical) MECHANISM OF ACTION Long-acting amylin analog

Peptide-mediated biomimetic regrowth of human enamel in situ

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