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Average weight loss accelerates between weeks 4 and 12, with many users reporting 5-10 pounds of loss during this period

Active cancer or history of malignancy Pregnancy or breastfeeding Known peptide allergies Athletes subject to anti-doping testing (WADA prohibited) Raynauds disease or phenomenon Cold urticaria (hives from cold) Uncontrolled hypertension Peripheral vascular disease Open wounds (for local application) Pregnancy Cardiovascular conditions Diabetes (especially with neuropathy) Current infections Immunosuppression Blood clotting disorders Quality control issues represent perhaps the greatest practical risk with BPC-157

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Liraglutide has also been seen to inhibit tau-hyperphosphorylation in DR, thus protecting RGCs from degeneration [91]