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Studies have shown that AOD9604 acts through a combination of pathways, including beta-3 adrenergic receptor upregulation, cAMP-PKA-HSL signaling pathway activation, and acetyl-CoA carboxylase inhibition

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On the other hand signalling molecules that operate mainly in the brain, in particular neuropeptide Y, brain-derived neurotrophic factor and -aminobutyric acid, which are disturbed by microbiological, obesity and diabetes, and are associated with psychiatric disorders (56, 57)

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