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Molecules 26 , 2340 (2021)

GHK-Cu peptide is a copper-binding peptide complex formed from GHK, a tripeptide made from glycine, histidine, and lysine, and copper ions 1, 9

Anyone with known copper metabolism issues should consult physicians before using copper peptides in any form

Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low