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When levels drop, joints may be more vulnerable to stiffness and limited movement

Proceedings of the National Academy of Sciences, 112(11), 34633468 Benedict C, Brooks SJ, ODaly OG, Almen MS, Morell A, berg K, Gingnell M, Schultes B, Hallschmid M, Broman JE, Larsson EM (2012) Acute sleep deprivation enhances the brains response to hedonic food stimuli: an fMRI study

For the latter, even a very strict diet only reduces the blood uric acid by about 1 mg/dL- not enough, in general, to keep uric acid from precipitating in the joints

Its essential to consult a healthcare provider before using any medication while pregnant