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In particular, human GBM and nasopharyngeal carcinoma cells with acquired radioresistance have high intracellular levels of Gln and increased activity of GS, necessary for nucleotide synthesis and efficient DNA repair [37]

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Unlike B12 deficiency, which produces well-recognised neurological and haematological manifestations, hypercobalaminaemia is typically asymptomatic

Identity, concentration, purity, sterility, endotoxins, and storage may be unreliable