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doi: 10.3389/fphar.2025.1708659 Received 19 September 2025 Revised 27 October 2025 Accepted 30 October 2025 Published 28 November 2025 Volume 16 - 2025 Edited by Ersilia Nigro, University of Campania Luigi Vanvitelli, Italy Reviewed by Burkhard Poeggeler, University of Gttingen, Germany Yuzhou Gui, Shanghai Xuhui Central Hospital, China Updates Copyright 2025 Hosseini, Abbaszadeh, Alavi, Gravandi, Amirian, Fakhri and Echeverra