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Improvements in ALT and AST liver enzymesmarkers of hepatic inflammationwere consistently observed across studies

Given the potential for heartburn to indicate underlying gastrointestinal issues and its impact on quality of life, individuals experiencing persistent heartburn should seek medical evaluation

Tirzepatide (MOUNJARO) is a once-weekly subcutaneous injectable agent first authorized for T2DM and later extended to the management of obesity or overweight with at least one weight-related comorbidity, thereby aligning its therapeutic scope with subcutaneous liraglutide and semaglutide [34,35,36]

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