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Cardiovascular symptoms : Call 999 or go to A&E if cold sensitivity is accompanied by chest pain, severe shortness of breath, palpitations, or swelling of the legs

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There was also a significant increase in the insulinogenic index in the high GLP-1 compared to the low GLP-1 group at 12 weeks [between group difference 17.9 (95% CI 1.76, 34.04)] ( Table 4 )

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