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Hydroquinone topical creams are the most clinically effective treatment for melasma, and are sometimes prescribed for sun spots and post-inflammatory hyperpigmentation from acne

Theyre considered to be long-term medications because they are treating a chronic condition of overweight or obesity, says Lofton

There are a few review papers out now that speak to their potential and how they need to be explored more for osteoarthritis, so I think it's definitely picking up