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What does the clinical evidence say about semaglutide's timeline

Along the gastrointestinal tract, both GPR 41 and 43 have been reported to be co-expressed, with FFAR2/GPR43 at higher levels and overall number of cells, especially intraepithelial leukocytes, while FFAR3/GPR42 is found on submucosal neurons [see Figure 3, (83, 295297)]