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Mechanistically, Drp1-associated mitochondrial fission facilitates the release of mtDNA and mitochondrial ROS (mtROS) into the cytoplasm, leading to the formation of inflammasomes within the myocardium and elevated transcription of pro-inflammatory factors, such as cysteine-3 and IL-18 [116]

It is a subject I am passionate about, and I personally teach the course to help prepare future practitioners for the rapidly evolving world of regenerative, functional, and longevity medicine

Biomed Pharmacother 150:113067