berberine with glp 1 Weight Loss Metabolic Support w/ Probiotics Resveratrol 60Caps Berberine activated GLP-1/GLP-1R/PKA signaling pathway

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Inhibiting inflammation can reduce neuronal cell toxicity, improve neuronal apoptosis and neurofunctional impairment, enhance learning and memory abilities, and alleviate symptoms of epilepsy (Reference Dey, Kang and Qiu36)

For the IV regimen, a loading dose of 150 mg/kg in 200 cc is given for 15 minutes, followed by 50 mg/kg in 500 cc over 4 hours and then 100 mg/kg in 1000 cc over 16 hours.4,54,56,71 For the PO regimen, a loading dose of 140 mg/kg is given, followed by 70 mg/kg every 4 hours for a total of 18 total doses.54,56,71 Renal or hepatic dose adjustment is unnecessary