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The protein components of the GCC are the actual glycine decarboxylase subunit (identified as the P subunit: pyridoxal phosphate-dependent), a lipoic acid-containing subunit (the H subunit), a tetrahydrofolate-requiring enzyme called aminomethyltransferase (the T subunit), and dihydrolipoamide dehydrogenase (the L subunit)

38 The p120 conditional knockout (KO) mice die young (within 21 days of their birth) and demonstrate progressive mucosal erosion and terminal bleeding, similar to what is observed in the dominant-negative cadherin mouse model of colitis and associated cancer, as described above

J Mass Spectrom 41, 332-8 (2006)