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For patients who have significant needle anxiety or strongly prefer oral medications, this availability difference can be the deciding factor between the two classes

Tirzepatide (Mounjaro, Zepbound) Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it targets two incretin receptors instead of one

While tirzepatide is a gold-standard diabetes treatment right now, retatrutides multi-pathway profile suggests it could offer an equally powerful, if not uniquely specialized, alternative for severe insulin resistance and advanced metabolic syndrome once approved

A: The Bridge applies to eligible Medicare Part D enrollees who are prescribed a GLP-1 specifically for obesity treatment