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RGN-259 treatment promoted rapid healing of corneal epithelial defects, improved Mackie classification disease stage, and produced significant improvements in ocular discomfort, foreign body sensation, and dryness, with no significant adverse effects

Nutritional Prevention of Cancer Study Group

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Severe liver or kidney disease: Impaired detoxification or renal clearance can lead to inefficient metabolism of NAD+, causing unpredictable systemic effects

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