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Severe nausea during the first injection typically indicates the liver is processing methionine and methylcobalamin faster than gastric motility can compensate

In the 72-week trial, people were able to lose an average of the following percentage of weight: 5 mg dose: 15% weight loss 10 mg dose: 20% weight loss 15 mg dose: 21% weight loss For someone starting at 200 pounds, this translates to approximately: 5 mg: 30 pounds lost 10 mg: 39 pounds lost 15 mg: 42 pounds lost While higher doses typically lead to greater weight loss, they also increase the likelihood of side effects, so your provider will carefully balance effectiveness with comfort

For people who need to avoid hypoglycemia (low blood sugar), a GLP-1 agonist may be beneficial, as it doesnt require manually calculating the right insulin dose

Typically, your doctor begins with a low dose and slowly raises it over weeks or months